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STEM CELL CULTURE SUPERNATANT THERAPY

“Full-body Rejuvenation”
Aging Care from the Cellular Level

Stem Cell Culture Supernatant Therapy utilizes the nutrient-rich fluid derived from stem cell cultivation, packed with regenerative factors to rejuvenate and repair the body at a cellular level. This supernatant is rich in proteins such as cytokines and growth factors that support tissue regeneration and the recovery of cellular function, playing an important role in cellular rejuvenation.

Administration time15 minutes
Infusion time1 hour
Local injection30 to 45 minutes
Interval30 to 60 days

The treatment interval may vary under the guidance of the attending physician.

Treatment Flow

STEP1. Consultation

There may be a need for imaging diagnostics, so please bring any previous medical records or images such as CT or MRI scans.

STEP2. Administration (Treatment)

Administration methods
Intravenous injection – Infusion
Subcutaneous injection – Abdomen or buttocks
Local injection – Scalp, face, neck
Joints – MRI imaging may be conducted depending on the case (30 minutes)

 

About Subcutaneous Injection

What is subcutaneous injection ?

Subcutaneous injection is a method of administering a shot
under the skin, in the subcutaneous tissue, similar to a
vaccination. Compared to intramuscular injections, it causes less
pain. Since the subcutaneous tissue has fewer blood vessels,
absorption is slower, and the blood concentration remains stable
and gradually effective for a longer period. As a result, the
medication stays at the site temporarily, which may cause a
temporary swelling.

What is Stem Cell Culture Supernatant?

Stem cell culture supernatant is the clarified liquid (supernatant) obtained after culturing human stem cells in a liquid medium. This supernatant is rich in various cytokines secreted by the stem cells. Cytokines are proteins secreted by cells that regulate cell growth and differentiation, playing a crucial role in restoring the function of damaged tissues and cells in the body. Since culture supernatant rich in cytokines supports the recovery of cells weakened by aging and other factors, it is expected to provide a wide range of health and beauty benefits.

  1. 01

Potential of Stem Cell Culture Supernatant

Stem cell culture supernatant is the liquid secreted
during the cultivation of stem cells and is rich in
bioactive substances such as growth factors and
cytokines. This promotes cellular regeneration and
repair, with expected benefits in chronic pain, atopic
dermatitis, autoimmune diseases, and more. It has
gained attention in regenerative medicine, cosmetic
treatments, and anti-inflammatory therapies. Its
practical applications are expanding, particularly in
the following areas:

Types of Stem Cell Culture Supernatant

At our clinic, we offer treatments using six types of stem cell culture supernatant. We are able to recommend the most appropriate option based on each patient’s concerns and objectives.

1. Amniotic Membrane

  • Characteristics: A thin membrane that forms part of the placenta, surrounding the fetus and retaining amniotic fluid.
  • Components: Composed of protein layers such as collagen, laminin, and nidogen.

2. Placenta

  • Characteristics: An organ that connects the mother and fetus and plays an essential role in sustaining life.
  • Function: Supplies nutrients and oxygen to the fetus and transfers waste products from the fetus to the mother.

3. Bone Marrow

  • Characteristics: Rich in growth factors and widely applied in tissue regeneration and disease treatment.
  • Effects: Promotes cell proliferation and repair, suppresses inflammation, and regulates immune responses.

4. Cord Blood

  • Characteristics: Blood remaining in the placenta and umbilical cord after childbirth.
  • Components: Contains a high concentration of stem cells that support the development of organs, muscles, bones, nerves, and blood components.

5. Dental Pulp

  • Characteristics: The tissue located at the center of the tooth, commonly referred to as the dental nerve.
  • Expected Potential: Capable of differentiating into nerve cells and expected to exhibit high neuroregenerative potential.

6. Adipose Tissue

  • Characteristics: Stem cells can be easily harvested and are also utilized in cosmetics such as serums and creams.
  • Effects: Exhibits strong angiogenic and tissue repair capabilities, contributing to improved blood flow and recovery of damaged tissues.

Stem Cell & Component–Based Total Care

1. Skin Anti-Aging (Improvement of Skin Aging)

Enhances the skin’s barrier function and normalizes cellular turnover.

  • Components Used: Amniotic membrane, cord blood, epithelial cells, fibroblasts
  • Main Effects: * Improvement of skin aging, enhancement of barrier function and reduction of inflammation
    • Normalization of skin turnover

2. Total Anti-Aging (Whole-Body Rejuvenation)

Reactivates cellular vitality throughout the body, aiming for comprehensive rejuvenation.

  • Cocktail Examples: * Placenta + Amniotic membrane
    • Placenta + Cord blood
    • Placenta + (Adipose or Cord blood cocktail)
  • Main Effects: Restoration of cellular activity and comprehensive anti-aging care

3. Improvement and Prevention of Paralysis and Dementia Progression

A specialized approach focused on nerve cell repair and improvement of blood circulation.

  • Components Used: Amniotic membrane, dental pulp
  • Cocktail Example: Dental pulp + Cord blood cocktail
  • Main Effects: * Promotion of nerve cell proliferation and repair
    • Improved blood flow and suppression of disease progression

4. Improvement of Atopic Dermatitis and Frailty

Suppresses inflammation and restores diminished physical functions.

  • Components Used: Amniotic membrane, cord blood, bone marrow, adipose tissue
  • Cocktail Examples: * Bone marrow + (Amniotic membrane or Cord blood cocktail)
    • Cord blood + Placenta cocktail
  • Main Effects: Reduction of inflammation, nerve repair, and improvement of frailty (age-related weakness)

5. Pain Relief and Osteoporosis

Addresses joint and bone issues such as lower back pain and knee pain.

  • Components Used: Dental pulp, adipose tissue, cord blood, amniotic membrane
  • Cocktail Example: Dental pulp + (Adipose or Cord blood cocktail)
  • Main Effects: Pain relief, support of bone density, and tissue repair

6. Hair Growth, Hair Regeneration, and ED Improvement

Promotes blood circulation and activates cell division and neural signaling.

  • Components Used: Dental pulp, placenta
  • Cocktail Example: Dental pulp + Placenta cocktail
  • Main Effects: * Hair Growth: Promotion of hair follicle cell division and increased FGF-7 (growth factor)
    • ED Improvement: Improved blood flow, vasodilation, and enhanced signal transmission

Case Photos

【Treatment Details】
Amniotic Membrane-Derived Stem Cell Culture Supernatant
3 sessions (Subcutaneous injection)

BEFORE

AFTER

【Progress】

A patient suffering from severe atopic dermatitis. After the first treatment, skin turnover was accelerated, and there was temporary peeling. However, after the second session, the symptoms of atopic dermatitis began to improve.

【Treatment Details】
Umbilical Cord Blood-Derived Stem Cell Culture Supernatant
3 sessions (Subcutaneous injection)
Umbilical Cord Blood-Derived Stem Cell Culture Supernatant Minoxidil Scalp Injection (Mesotherapy) 3 sessions

BEFORE

AFTER

【Progress】

The patient was concerned about thinning hair on the crown. Initially, the supernatant was locally injected to maintain the
current condition. After adding Minoxidil, the hair volume and density increased with three injections, and the hair is now noticeably less sparse.

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